Lacutoclax | Bcl-2 inhibitor | Probechem Biochemicals

Chemical Structure : Lacutoclax

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Lacutoclax (LP-108, LP108)

货号: PC-23094Not For Human Use, Lab Use Only.

Lacutoclax (LP-108) is a highly potent and selective inhibitor of BCL-2 with comparable or more potent in vitro inhibitory activity compared to venetoclax.

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生物&药学活性

Lacutoclax (LP-108) is a highly potent and selective inhibitor of BCL-2 with comparable or more potent in vitro inhibitory activity compared to venetoclax.

物理化学性质&存储条件

分子量	923.53
分子式	C48H55ClN8O7S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-2-[(3R)-2,3-dihydro-3-methylpyrrolo[3′,2′:5,6]pyrido[2,3-b][1,4]oxazin-1(6H)-yl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]benzamide

参考文献

1. Patent WO2021066873 A1 2021-04-08.

Lacutoclax (LP-108, LP108)

生物&药学活性

物理化学性质&存储条件

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Lacutoclax (LP-108, LP108)

生物&药学活性

物理化学性质&存储条件

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