LYPLAL1-IN-11 |CAS:1966129-74-7 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-LYPLAL1-IN-11

Chemical Structure : LYPLAL1-IN-11

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LYPLAL1-IN-11

货号: PC-62407Not For Human Use, Lab Use Only.

LYPLAL1-IN-11 is a potent, selective, covalent inhibitor of lysophospholipase-like 1 (LYPLAL1) with IC50 of 6 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LYPLAL1-IN-11 is a potent, selective, covalent inhibitor of lysophospholipase-like 1 (LYPLAL1) with IC50 of 6 nM.
LYPLAL1-IN-11 displays high selectivity against a panel of the broader human serine hydrolase proteome (>30 enzymes).
LYPLAL1-IN-11 significant increases glucose production in human, rat, mouse hepatocytes.

物理化学性质&存储条件

分子量	539.596
分子式	C29H29N7O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R)-1-(3-(4-(2-morpholinopyrimidin-5-yl)phenyl)-1H-1,2,4-triazole-1-carbonyl)-2-phenylpiperidine-3-carboxylic acid

参考文献

1. Ahn K, et al. ACS Chem Biol. 2016 Sep 16;11(9):2529-40.

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LYPLAL1-IN-11

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LYPLAL1-IN-11

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