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首页-小分子抑制剂&激动剂-Others-Other Targets-LY3475070
LY3475070

Chemical Structure : LY3475070

CAS No.: 2375815-63-5

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LY3475070 (LY-3475070)

货号: PC-38017Not For Human Use, Lab Use Only.

LY3475070 (LY-3475070) is a potent, selective and orally bioavailable inhibitor of the ectoenzyme CD73 with IC50 of 28 nM, targeting the adenosine pathway against the tumor microenvironment.

规格 价格 库存 数量
5 mg ￥1980 In stock
25 mg ￥3980 In stock
50 mg ￥5980 In stock
100 mg ￥9980 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LY3475070 (LY-3475070) is a potent, selective and orally bioavailable inhibitor of the ectoenzyme CD73 with IC50 of 28 nM, targeting the adenosine pathway against the tumor microenvironment.

物理化学性质&存储条件

分子量 286.335
分子式 C15H18N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-(5-((1S,2R)-2-isopropylcyclopropyl)-6-methylpyridazin-3-yl)pyrimidine-2,4(1H,3H)-dione

参考文献

1. Elizabeth A. Thompson, et al. Annu Rev Med. 2022 Jan 27.

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