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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-LY3405105
LY3405105

Chemical Structure : LY3405105

CAS No.: 2326428-25-3

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LY3405105 (LY-3405105)

货号: PC-72467Not For Human Use, Lab Use Only.

LY3405105 (LY-3405105) is a potent, selective, orally active CDK7 inhibitor with an IC50 of 92.8 nM, shows potential antineoplastic activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    LY3405105 (LY-3405105) is a potent, selective, covalent and orally active CDK7 inhibitor with an IC50 of 92.8 nM, shows potential antineoplastic activity.

    物理化学性质&存储条件

    分子量 497.644
    分子式 C26H39N7O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester

    参考文献

    1. Georgina P Sava, et al. Cancer Metastasis Rev. 2020 Sep;39(3):805-823.

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