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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-LY334370
LY334370

Chemical Structure : LY334370

CAS No.: 182563-08-2

LY334370 (LY-334370)

货号: PC-25708Not For Human Use, Lab Use Only.

LY334370 is a high-affinity, selective serotonin 5-HT1F receptor agonist withEC50 of 2.13 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LY334370 is a high-affinity, selective serotonin 5-HT1F receptor agonist withEC50 of 2.13 nM and Ki of 1.6 nM.

物理化学性质&存储条件

分子量 351.43
分子式 C21H22FN3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benzamide

参考文献

1. Dupuis DS, et al. Br J Pharmacol. 1998 May;124(2):283-90.

2. Wainscott DB, et al. Eur J Pharmacol. 1998 Jul 3;352(1):117-24.

3. Johnson KW, et al. Neuroreport. 1997 Jul 7;8(9-10):2237-40.

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