LY3130481 (CERC611) |CAS:1610802-47-5 Probechem Biochemicals

Chemical Structure : LY3130481

CAS No.: 1610802-47-5

加入收藏

LY3130481 (LY-3130481, CERC-611, CERC611)

货号: PC-60899Not For Human Use, Lab Use Only.

LY3130481 (CERC611) is a potent, selective, noncompetitive TARP γ8-associated AMPA receptors with IC50 of 65.3 nM (GluA1/TARP γ-8), with no activity for γ-2 (cerebellum) or other TARP members.

规格	价格	库存
5 mg	￥3280	In stock
10 mg	￥5280	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

LY3130481 (CERC611) is a potent, selective, noncompetitive TARP γ8-associated AMPA receptors antagonist with IC50 of 65.3 nM (GluA1/TARP γ-8), with no activity for γ-2 (cerebellum) or other TARP members.
LY3130481 (CERC611) demonstrates fully protective against pentylenetetrazole-induced convulsions in rats without the motor impairment associated with non-TARP-dependent AMPA receptor antagonists.

物理化学性质&存储条件

分子量	382.438
分子式	C19H18N4O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-6-(1-(1-(5-(2-hydroxyethoxy)pyridin-2-yl)-1H-pyrazol-3-yl)ethyl)benzo[d]thiazol-2(3H)-one

参考文献

1. Gardinier KM, et al. J Med Chem. 2016 May 26;59(10):4753-68.

2. Kato AS, et al. Nat Med. 2016 Dec;22(12):1496-1501.

3. Witkin JM, et al. Neuropharmacology. 2017 Nov;126:257-270.

LY3130481 (LY-3130481, CERC-611, CERC611)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

LY3130481 (LY-3130481, CERC-611, CERC611)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.