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首页-小分子抑制剂&激动剂-Immunology/Inflammation-PGE synthase-LY3023703
LY3023703

Chemical Structure : LY3023703

CAS No.: 1415089-24-5

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LY3023703 (LY 3023703)

货号: PC-38689Not For Human Use, Lab Use Only.

LY3023703 is a potent, highly selective microsomal prostaglandin E synthase 1 (mPGES1) inhibitor, dose-dependently inhibits PGE2 production in human whole blood ex vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    LY3023703 is a potent, highly selective microsomal prostaglandin E synthase 1 (mPGES1) inhibitor, dose-dependently inhibits PGE2 production in human whole blood ex vivo.

    物理化学性质&存储条件

    分子量 495.454
    分子式 C23H22F5N5O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(Difluoromethyl)-5-[[(2-methyl-1-oxopropyl)amino]methyl]-N-[4-methyl-5-[4-(trifluoromethyl)phenyl]-1H-imidazol-2-yl]-3-pyridinecarboxamide

    参考文献

    1. Norman BH, et al. J Med Chem. 2018 Mar 8;61(5):2041-2051.

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