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首页-小分子抑制剂&激动剂-GPCR-mGluR-LY2979165
LY2979165

Chemical Structure : LY2979165

CAS No.: 311385-35-9

LY2979165 (MP-101, LY-2979165)

货号: PC-62593Not For Human Use, Lab Use Only.

LY2979165 (MP-101) is the alanine prodrug of LY2812223, a selective orthosteric mGlu2 receptor agonist.

规格 价格 库存 数量
5 mg ¥1380 In stock
10 mg ¥2180 In stock
25 mg ¥3580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LY2979165 (MP-101) is the alanine prodrug of LY2812223, a selective orthosteric mGlu2 receptor agonist.
LY2979165 suppresses glutamate release at presynaptic receptors during periods of enhanced, abnormal, glutamate activity and has potential for use in treating psychiatric and neurologic disorders

物理化学性质&存储条件

分子量 355.369
分子式 C13H17N5O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,2S,4R,5R,6R)-4-((4H-1,2,4-triazol-3-yl)thio)-2-((S)-2-aminopropanamido)bicyclo[3.1.0]hexane-2,6-dicarboxylic acid

参考文献

1. McColm J, et al. Br J Clin Pharmacol. 2017 Aug;83(8):1654-1667.

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