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首页-小分子抑制剂&激动剂-GPCR-mGluR-LY2794193
LY2794193

Chemical Structure : LY2794193

CAS No.: 2173037-97-1

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LY2794193 (LY-2794193)

货号: PC-63236Not For Human Use, Lab Use Only.

LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor.

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10 mg ￥5780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LY2794193 is a highly potent and selective mGlu3 receptor agonist with Ki of 0.93 nM and EC50 of 47 nM, >100-fold selectivity over mGlu2 receptor.

物理化学性质&存储条件

分子量 334.328
分子式 C16H18N2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1S,2S,4S,5R,6S)-2-Amino-4-[(3-methoxybenzoyl)amino]bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid

参考文献

1. Monn JA, et al. J Med Chem. 2018 Mar 22;61(6):2303-2328.

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