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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Glucokinase-LY2608204
LY2608204

Chemical Structure : LY2608204

CAS No.: 1234703-40-2

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LY2608204 (Globalagliatin, LY-2608204)

货号: PC-49836Not For Human Use, Lab Use Only.

Globalagliatin (LY2608204) is a potent, small molecule activator of glucokinase (GK) with EC50 value of 42 nM.

规格 价格 库存 数量
5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3480 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Globalagliatin (LY2608204) is a potent, small molecule activator of glucokinase (GK) with EC50 value of 42 nM.
Globalagliatin (LY2608204) induces glucose metabolism and reduces glucose levels for the treatment of type 2 diabetes.

物理化学性质&存储条件

分子量 559.80
分子式 C28H37N3O3S3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
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Solubility

10 mM in DMSO
Chemical Name/SMILES

(1R,2S)-2-Cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]cyclopropanecarboxamide

参考文献

1. Zheng S, et al. Clin Drug Investig. 2020 Dec;40(12):1155-1166

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