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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-LY255582
LY255582

Chemical Structure : LY255582

CAS No.: 119193-09-8

LY255582 (LY 255582)

货号: PC-20520Not For Human Use, Lab Use Only.

LY255582 is a potent, pan-opioid antagonist with Ki value of for 0.4 nM, 5.2 nM and 2.0 nMmu, delta, and kappa receptors, respectively, decreases short- and long-term food intake in rats.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LY255582 is a potent, pan-opioid antagonist with Ki value of for 0.4 nM, 5.2 nM and 2.0 nMmu, delta, and kappa receptors, respectively, decreases short- and long-term food intake in rats.

物理化学性质&存储条件

分子量 345.53
分子式 C22H35NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

OC1=CC([C@@]2(C)[C@@H](C)CN(CC[C@H](O)C3CCCCC3)CC2)=CC=C1

参考文献

1. Levine AS, et al. Brain Res. 1991 Dec 6;566(1-2):193-7.

2. Shaw WN, et al. Pharmacol Biochem Behav. 1993 Nov;46(3):653-9.

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