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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-LY2444296
LY2444296

Chemical Structure : LY2444296

CAS No.: 1346133-11-6

LY2444296 (FP3FBZ, LY-2444296)

货号: PC-22000Not For Human Use, Lab Use Only.

LY2444296 is a potent, selective orally bioavailable, and short-acting kappa opioid receptor (KOPR) antagonist with Ki of 1 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LY2444296 is a potent, selective orally bioavailable, and short-acting kappa opioid receptor (KOR) antagonist with Ki of 1 nM.

物理化学性质&存储条件

分子量 408.45
分子式 C24H22F2N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-3-fluoro-4-(4-((2-(3-fluorophenyl)pyrrolidin-1-yl)methyl)phenoxy)benzamide

参考文献

1. Huang P, et al. Eur J Pharmacol. 2016 Jun 15;781:53-9.

2. Huang P, et al. Neurosci Lett. 2016 Feb 26;615:15-20.

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