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首页-小分子抑制剂&激动剂-Others-Other Targets-LSN3374443
LSN3374443

Chemical Structure : LSN3374443

CAS No.: 2565658-29-7

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LSN3374443 (LSN-3374443)

货号: PC-24909Not For Human Use, Lab Use Only.

LSN3374443 is a potent, dimeric apolipoprotein(a) (apo(a)) binder and inhibitor of Lipoprotein(a) (Lp(a)) formation, disrupts the formation of Lp(a) with IC50 of 36 nM in in vitro Lp(a) assembly assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LSN3374443 is a potent, dimeric apolipoprotein(a) (apo(a)) binder and inhibitor of Lipoprotein(a) (Lp(a)) formation, disrupts the formation of Lp(a) with IC50 of 36 nM in in vitro Lp(a) assembly assays.

物理化学性质&存储条件

分子量 409.49
分子式 C23H27N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-3-(3-(3-(3-methoxyphenyl)-2-oxoimidazolidin-1-yl)phenyl)-2-((R)-pyrrolidin-3-yl)propanoic acid

参考文献

1. Nuria Diaz, et al. Nature. 2024 May;629(8013):945-950.

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