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首页-小分子抑制剂&激动剂-Epigenetics-Histone Demethylase-LSD1 inhibitor CHBH
LSD1 inhibitor CHBH

Chemical Structure : LSD1 inhibitor CHBH

CAS No.: 1423715-06-3

LSD1 inhibitor CHBH

货号: PC-27603Not For Human Use, Lab Use Only.

CHBH is a lysine-specific histone demethylase 1A (LSD1, KDM1A) inhibitor, does not act on KDM4A, reduces the viability of a panel of cancer cell lines with IC50 values in the micromolar range.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

CHBH is a lysine-specific histone demethylase 1A (LSD1, KDM1A) inhibitor, does not act on KDM4A, reduces the viability of a panel of cancer cell lines with IC50 values in the micromolar range.

物理化学性质&存储条件

分子量 274.70
分子式 C14H11ClN2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-chloro-N'-(2-hydroxybenzylidene)benzohydrazide

参考文献

1. Venkataswamy Sorna, et al. J Med Chem. 2013 Dec 12;56(23):9496-508.

2. Federica Sarno, et al. Front Pharmacol. 2018 Sep 7:9:1006.

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