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LSALT peptide

Chemical Structure : LSALT peptide

CAS No.: 2567713-50-0

LSALT peptide (Metablok)

货号: PC-38773Not For Human Use, Lab Use Only.

Metablok (LSALT peptide) is a specific DPEP1-binding peptide and nonenzymatic dipeptidase-1 (DPEP-1) inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Metablok (LSALT peptide) is a specific DPEP1-binding peptide and nonenzymatic dipeptidase-1 (DPEP-1) inhibitor.
    LSALT peptide binds specifically to DPEP1 with no detectable binding to DPEP2 or DPEP3.
    LSALT peptide significantly reduces neutrophil recruitment to the lungs and liver and provides improved survival in models of endotoxemia.
    LSALT peptide boclks neutrophil adhesion to peritubular capillaries and reduces inflammatory monocyte recruitment to the kidney after IRI.

    物理化学性质&存储条件

    分子量 1774.14
    分子式 C85H136N20O21
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    H-LSALTPSPSWLKYKAL-NH2

    参考文献

    1. Arthur Lau, et al. Sci Adv. 2022 Feb 4;8(5):eabm0142.

    2. Choudhury S. R., et al. Cell. 178, 1205-1221.e17 (2019).

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