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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Notum-LP-922056
LP-922056

Chemical Structure : LP-922056

CAS No.: 1365060-22-5

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LP-922056 (LP922056)

货号: PC-72826Not For Human Use, Lab Use Only.

LP-922056 (LP922056) is a potent Notum inhibitor with IC50 of 1.1 nM in OPTS assays.

规格 价格 库存 数量
10 mg ￥880 In stock
25 mg ￥1480 In stock
50 mg ￥2380 In stock
100 mg ￥3880 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LP-922056 (LP922056) is a potent Notum inhibitor with IC50 of 1.1 nM in OPTS assays.
LP-922056 is a valuable chemical tool for exploring the role of Notum in Wnt signaling at a cellular level and for use in animal disease models.

物理化学性质&存储条件

分子量 300.775
分子式 C11H9ClN2O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((6-Chloro-7-cyclopropylthieno[3,2-d]pyrimidin-4-yl)thio)acetic acid

参考文献

1. Elliott D Bayle, et al. J Med Chem. 2021 Apr 22;64(8):4289-4311.

2. Zhao Y, et al. Future Med Chem. 2021 Jun;13(11):1001-1015.

3. James E Tarver Jr, et al. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1525-1528.

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