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LJ001

Chemical Structure : LJ001

CAS No.: 851305-26-5

LJ001 (LJ-001)

货号: PC-62050Not For Human Use, Lab Use Only.

LJ001 ((LJ-001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1.

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10 mg ¥2180 In stock
25 mg ¥3780 In stock
50 mg ¥5880 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LJ001 ((LJ-001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1.
LJ001 specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion.
LJ001 specifically inhibits virus-cell but not cell-cell fusion

物理化学性质&存储条件

分子量 327.42
分子式 C17H13NO2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(5Z)-5-[(5-phenylfuran-2-yl)methylidene]-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one

参考文献

1. Wolf MC, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62.

2. Vigant F, et al. PLoS Pathog. 2013;9(4):e1003297.

3. Balmer BF, et al. J Virol. 2017 Jan 31;91(4). pii: e02181-16.

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