Chemical Structure : LJ001
CAS No.: 851305-26-5
货号: PC-62050Not For Human Use, Lab Use Only.
LJ001 ((LJ-001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1380 | In stock | |
10 mg | ¥2180 | In stock | |
25 mg | ¥3780 | In stock | |
50 mg | ¥5880 | In stock | |
100 mg | Get quote |
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LJ001 ((LJ-001) is a broad-spectrum antiviral agent targeting entry of enveloped viruses, including influenza A, filoviruses, poxviruses, arenaviruses, bunyaviruses, paramyxoviruses, flaviviruses, and HIV-1.
LJ001 specifically intercalates into viral membranes, irreversibly inactivates virions while leaving functionally intact envelope proteins, and inhibits viral entry at a step after virus binding but before virus-cell fusion.
LJ001 specifically inhibits virus-cell but not cell-cell fusion
分子量 | 327.42 | |
分子式 | C17H13NO2S2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(5Z)-5-[(5-phenylfuran-2-yl)methylidene]-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one |
1. Wolf MC, et al. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3157-62.
2. Vigant F, et al. PLoS Pathog. 2013;9(4):e1003297.
3. Balmer BF, et al. J Virol. 2017 Jan 31;91(4). pii: e02181-16.
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