LJ-5242 | HASPIN inhibitor | Probechem Biochemicals

Chemical Structure : LJ-5242

加入收藏

LJ-5242 (LJ5242)

货号: PC-27066Not For Human Use, Lab Use Only.

LJ-5242 is a selective, ATP-mimicking inhibitor of atypical serine/threonine kinase haploid germ cell-specific nuclear protein kinase (HASPIN) with MST Kd of 23.1 nM, and IC50 of 1.1 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

LJ-5242 is a selective, ATP-mimicking inhibitor of atypical serine/threonine kinase haploid germ cell-specific nuclear protein kinase (HASPIN) with MST Kd of 23.1 nM, and IC50 of 1.1 nM.
LJ-5242 binds to the ATP-binding pocket of HASPIN in an ATP-like orientation.
LJ-5242 displays >1000-fold selectivity over FYN, PAK4, and TYK2 kinases.
LJ-5242 potently suppresses cellular proliferation in cancer cell strains, human lung cancer cell line A549 and human colon cancer cell line HCT116.

物理化学性质&存储条件

分子量	384.43
分子式	C13H16N6O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O[C@@H]1[C@H](O)[C@@H](CNS(=O)(N)=O)S[C@H]1N2C=C(C#C)C3=C(N)N=CN=C32

参考文献

1. Cheon SW, et al. Sci Rep. 2026 Jun 14. doi: 10.1038/s41598-026-57282-y.

LJ-5242 (LJ5242)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

LJ-5242 (LJ5242)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.