LIT-001 trifluoroacetate | OXTR agonist | Probechem Biochemicals

Chemical Structure : LIT-001 trifluoroacetate

CAS No.: 2245072-21-1

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LIT-001 trifluoroacetate (LIT001)

货号: PC-35700Not For Human Use, Lab Use Only.

LIT-001 trifluoroacetate (LIT001) is the first nonpeptide Oxytocin receptor (OT-R) agonist with EC50 of 55 nM, Emax=96%.

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10 mg	￥1480	In stock
25 mg	￥2580	In stock
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生物&药学活性

LIT-001 trifluoroacetate (LIT001) is the first nonpeptide Oxytocin receptor (OT-R) agonist with EC50 of 55 nM, Emax=96%.
LIT-001 efficiently relieved social interaction deficits in Oprm1−/− mice, a mouse model of autism.

物理化学性质&存储条件

分子量	645.702
分子式	C30H34F3N7O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(Dimethylcarbamothioyl)-N-(2-methyl-4-(1-methyl1,4,5,10-tetrahydrobenzo[b]pyrazolo[3,4-e][1,4]diazepine-5- carbonyl)benzyl)pyrrolidine-1-carboxamide, trifluoroacetate

参考文献

1. Frantz MC, et al. J Med Chem. 2018 Oct 11;61(19):8670-8692.

LIT-001 trifluoroacetate (LIT001)

生物&药学活性

物理化学性质&存储条件

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LIT-001 trifluoroacetate (LIT001)

生物&药学活性

物理化学性质&存储条件

参考文献

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