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首页-小分子抑制剂&激动剂-Others-Other Targets-LIN28 inhibitor LI71
LIN28 inhibitor LI71

Chemical Structure : LIN28 inhibitor LI71

CAS No.: 1357248-83-9

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LIN28 inhibitor LI71 (LI71)

货号: PC-35201Not For Human Use, Lab Use Only.

LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 7 uM, binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells.

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5 mg ￥2480 In stock
10 mg ￥3980 In stock
25 mg ￥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LIN28 inhibitor LI71 is a potent, cell-permeable inhibitor of LIN28 that abolishes LIN28-mediated oligouridylation with IC50 of 7 uM, binds the cold shock domain to suppress LIN28's activity against let-7 in leukemia cells and embryonic stem cells.

物理化学性质&存储条件

分子量 335.403
分子式 C21H21NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((3aS,4R,9bR)-6-ethoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl)benzoic acid

参考文献

1. Wang L, et al. Cell Rep. 2018 Jun 5;23(10):3091-3101.

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