LEM-14 | NSD2 inhibitor | Probechem Biochemicals

Chemical Structure : LEM-14

CAS No.: 1814881-70-3

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LEM-14 (NSD2 inhibitor LEM14)

货号: PC-35849Not For Human Use, Lab Use Only.

LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.

规格	价格	库存
5 mg	￥1680	In stock
10 mg	￥2880	In stock
25 mg	￥4880	In stock
100 mg		Get quote

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生物&药学活性

LEM-14 is a specific inhibitor of histone lysine methyltransferase NSD2 (MMSET/WHSC1) with in vitro IC50 of 132 uM, and that is inactive against the closely related NSD1 and NSD3.

物理化学性质&存储条件

分子量	478.567
分子式	C25H26N4O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-((4-(1-oxoisochromane-3-carbonyl)piperazin-1-yl)methyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one

参考文献

1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4.

LEM-14 (NSD2 inhibitor LEM14)

生物&药学活性

物理化学性质&存储条件

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LEM-14 (NSD2 inhibitor LEM14)

生物&药学活性

物理化学性质&存储条件

参考文献

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