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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-LEM-14-1189
LEM-14-1189

Chemical Structure : LEM-14-1189

CAS No.: 2987501-17-5

LEM-14-1189

货号: PC-35850Not For Human Use, Lab Use Only.

LEM-14-1189 is a LEM-14 derivative that differentially inhibits the NSDs with in vitro IC50 of 418 μM (NSD1), IC50 of 111 μM (NSD2) and IC50 of 60 μM (NSD3).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    LEM-14-1189 is a LEM-14 derivative that differentially inhibits the NSDs with in vitro IC50 of 418 μM (NSD1), IC50 of 111 μM (NSD2) and IC50 of 60 μM (NSD3).

    物理化学性质&存储条件

    分子量 682.814
    分子式 C35H34N6O5S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(3-(bis((4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)methyl)amino)propyl)-1-oxo-1H-isochromene-3-carboxamide

    参考文献

    1. Shen Y, et al. Biochem Biophys Res Commun. 2018 Nov 21. pii: S0006-291X(18)32443-4.

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