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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Glutaminase-LDN-27219
LDN-27219

Chemical Structure : LDN-27219

CAS No.: 312946-37-5

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LDN-27219 (LDN 27219, LDN 27219)

货号: PC-45039Not For Human Use, Lab Use Only.

LDN-27219 is a potent, reversible inhibitor of hTGase (Tissue transglutaminase) with IC50 of 0.8 uM.

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

LDN-27219 is a potent, reversible inhibitor of hTGase (Tissue transglutaminase) with IC50 of 0.8 uM.
LDN-27219 does not bind at the enzyme's active site but rather at the enzyme's GTP site, or a site that regulates binding of GTP.

物理化学性质&存储条件

分子量 408.4966
分子式 C20H16N4O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 4.3 mg/mL
Chemical Name/SMILES

Acetic acid, 2-[(3,4-dihydro-4-oxo-3,5-diphenylthieno[2,3-d]pyrimidin-2-yl)thio]-, hydrazide

参考文献

1. Duval E, et al. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1885-9.

2. Case A, et al. Biochemistry. 2007 Jan 30;46(4):1106-15.

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