LDN-214117 |CAS:1627503-67-6 Probechem Biochemicals

Chemical Structure : LDN-214117

CAS No.: 1627503-67-6

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LDN-214117 (LDN214117)

货号: PC-45058Not For Human Use, Lab Use Only.

LDN-214117 (LDN214117) is a potent and selective ALK2 inhibitor with a biochemical IC50 of 24 nM, a cell-based IC50 for BMP6 of 100 nM.

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10 mg	￥1180	In stock
25 mg	￥1980	In stock
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100 mg		Get quote

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生物&药学活性

LDN-214117 (LDN214117) is a potent and selective ALK2 inhibitor with a biochemical IC50 of 24 nM, a cell-based IC50 for BMP6 of 100 nM.
LDN-214117 displays 164-fold selectivity for BMP6 versus TGF-β1.
LDN-214117 is a highly selective probe of BMP-mediated cellular physiology.

物理化学性质&存储条件

分子量	419.5161
分子式	C25H29N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Piperazine, 1-[4-[6-methyl-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenyl]-

参考文献

1. Mohedas AH, et al. J Med Chem. 2014 Oct 9;57(19):7900-15.

LDN-214117 (LDN214117)

生物&药学活性

物理化学性质&存储条件

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LDN-214117 (LDN214117)

生物&药学活性

物理化学性质&存储条件

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