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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Lactate Dehydrogenase (LDH)-LDHA inhibitor 1g
LDHA inhibitor 1g

Chemical Structure : LDHA inhibitor 1g

CAS No.: 862719-04-8

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LDHA inhibitor 1g

货号: PC-23596Not For Human Use, Lab Use Only.

LDHA inhibitor 1g is a potent, selective inhibitor of lactate dehydrogenase A (LDHA) with IC50 of 25 nM, without affecting the LDH-B isoform (LDHB), inhibits the aerobic glycolytic phenotype of cancer metabolism.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LDHA inhibitor 1g is a potent, selective inhibitor of lactate dehydrogenase A (LDHA) with IC50 of 25 nM, without affecting the LDH-B isoform (LDHB), inhibits the aerobic glycolytic phenotype of cancer metabolism.

物理化学性质&存储条件

分子量 384.27
分子式 C17H22BrNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

methyl 4-bromo-3-[(n-hexyloxy)methyl]-1-hydroxy-1H-indole-2-carboxylate

参考文献

1. Cheon SY, et al. Eur J Med Chem. 2024 Nov 30;283:117104.

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