LDHA-IN-104 |CAS:1642114-19-9 Probechem Biochemicals

Chemical Structure : LDHA-IN-104

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LDHA-IN-104

货号: PC-62683Not For Human Use, Lab Use Only.

LDHA-IN-104 is a potent and selective lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.87 uM, less potent for LDHB (IC50=6.9 uM).

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生物&药学活性

LDHA-IN-104 is a potent and selective lactate dehydrogenase A (LDHA) inhibitor with IC50 of 0.87 uM, less potent for LDHB (IC50=6.9 uM).
LDHA-IN-104 exhibits good pharmacokinetic properties after oral administration to rats (F=45%).

物理化学性质&存储条件

分子量	399.71
分子式	C18H13Cl3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2',6'-dichloro-4-((2-chlorophenyl)thio)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one

参考文献

1. Dragovich PS, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3764-71.

LDHA-IN-104

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物理化学性质&存储条件

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LDHA-IN-104

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物理化学性质&存储条件

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