LC-YD17

Chemical Structure : LC-YD17

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货号: PC-27974Not For Human Use, Lab Use Only.

LC-YD17 is a potent, selective YTH domain-containing protein 1 (YTHDC1) inhibitor with IC50 of 107.12 nM, exhibits growth inhibitory activity in MOLM-13 and THP-1 cells with IC50 of 11.74 and 16.36 uM respectively.

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生物&药学活性

LC-YD17 is a potent, selective YTH domain-containing protein 1 (YTHDC1) inhibitor with IC50 of 107.12 nM, exhibits growth inhibitory activity in MOLM-13 and THP-1 cells with IC50 of 11.74 and 16.36 uM respectively.

物理化学性质&存储条件

分子量	465.95
分子式	C22H24ClN9O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-(4-((2-chloro-6-(methylamino)-9H-purin-9-yl)methyl)-1H-1,2,3-triazol-1-yl)phenyl)-1-(piperidin-1-yl)ethan-1-one

参考文献

1. Mingchen Wang, et al. Adv Sci (Weinh). 2026 Aug 27:e77386.

LC-YD17

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物理化学性质&存储条件

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LC-YD17

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