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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-p97/VCP-LC-1028
LC-1028

Chemical Structure : LC-1028

CAS No.: 2324158-08-7

LC-1028 (LC1028;LC 1028)

货号: PC-36136Not For Human Use, Lab Use Only.

LC-1028 (LC1028) is a novel potent selective, covalent and irreversible inhibitor of p97 (valosin-containing protein), remains essentially irreversible ac tivity against p97 mutant C522A..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

     (LC1028) is a novel potent selective, covalent and irreversible inhibitor of p97 (valosin-containing protein), remains essentially irreversible aciivity against p97 mutant C522A.

    物理化学性质&存储条件

    分子量 449.558
    分子式 C28H27N5O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(1-(4-(Benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl)-2-methyl-1H-indol-4-yl)but-2-ynamide

    参考文献

    1. Ding R, et al. J Med Chem. 2019 Mar 14;62(5):2814-2829.

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