LASV inhibitor 3.3 |CAS:554438-52-7 Probechem Biochemicals

Chemical Structure : LASV inhibitor 3.3

CAS No.: 554438-52-7

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LASV inhibitor 3.3 (LAMP1 inhibitor 3.3)

货号: PC-35712Not For Human Use, Lab Use Only.

LASV inhibitor 3.3 (LAMP1 inhibitor 3.3) is a specific inhibitor of Lassa fever virus (LASV, IC50=1.8 uM), inhibits LASV GP-mediated infection and cross-links to the LASV receptor, LAMP1, in cells.

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10 mg	￥1380	In stock
25 mg	￥2480	In stock
50 mg	￥3980	In stock
100 mg		Get quote

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生物&药学活性

LASV inhibitor 3.3 (LAMP1 inhibitor 3.3) is a specific inhibitor of Lassa fever virus (LASV, IC50=1.8 uM), inhibits LASV GP-mediated infection and cross-links to the LASV receptor, LAMP1, in cells.
LASV inhibitor 3.3 does not inhibits the GP-mediated infection of LCMV, LuJo virus (LUJV) or Junin virus (JUNV), Ebola virus (EBOV) or vesicular stomatitis virus (VSV).
LASV inhibitor 3.3 inhibits LAMP1 binding to LASV GP, which is cholesterol-dependent and sensitive to 3.3 inhibition.
LASV inhibitor 3.3 is a competitive inhibitor of cholesterol binding to LAMP1.

物理化学性质&存储条件

分子量	471.645
分子式	C30H37N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(4-benzhydrylpiperazin-1-yl)-2-oxoethyl)adamantane-1-carboxamide

参考文献

1. Wang MK, et al. PLoS Pathog. 2018 Sep 28;14(9):e1007322.

2. PCT Int. Appl. (2013), WO 2013022550 A2 20130214.

LASV inhibitor 3.3 (LAMP1 inhibitor 3.3)

生物&药学活性

物理化学性质&存储条件

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LASV inhibitor 3.3 (LAMP1 inhibitor 3.3)

生物&药学活性

物理化学性质&存储条件

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