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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-LASSBio-2337
LASSBio-2337

Chemical Structure : LASSBio-2337

CAS No.:

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LASSBio-2337

货号: PC-26400Not For Human Use, Lab Use Only.

LASSBio-2337 is a potent, dual pan-PI3K/mTOR inhibitor with IC50 of 0.3, 4.2, 0.6, 7.5 and 5.8 uM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR respectively, shows cytotoxic effects in leukemia cell lines with CC50 of 4.37-9.44 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

LASSBio-2337 is a potent, dual pan-PI3K/mTOR inhibitor with IC50 of 0.3, 4.2, 0.6, 7.5 and 5.8 uM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR respectively, shows cytotoxic effects in leukemia cell lines with CC50 of 4.37-9.44 uM.

物理化学性质&存储条件

分子量 356.43
分子式 C18H24N6O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(4-(1,4-Diazepan-1-yl)-6-morpholino-1,3,5-triazin-2-yl) Phenol

参考文献

1. Aparecida E Silva C, et al. ACS Omega. 2026 Feb 5;11(6):9719-9733.

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