L 741742 hydrochloride |CAS:874882-93-6 Probechem Biochemicals

Chemical Structure : L 741742 hydrochloride

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L 741742 hydrochloride (L-741742;L741,742;L741742)

货号: PC-60615Not For Human Use, Lab Use Only.

A potent and highly selective D4 dopamine receptor antagonist with Ki of 3.5 nM, >200-fold selectivity over D2 and D3 receptors.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

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生物&药学活性

A potent and highly selective D4 dopamine receptor antagonist with Ki of 3.5 nM, >200-fold selectivity over D2 and D3 receptors; also selectively inhibits GBM neural stem cells (GNS) growth and promotes differentiation of normal neural stem cells.

物理化学性质&存储条件

分子量	417.38
分子式	C23H25N2ClO.HCl
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole hydrochloride

参考文献

1. Rowley M, et al. J Med Chem. 1996 May 10;39(10):1943-5.

2. Dolma S, et al. Cancer Cell. 2016 Jun 13;29(6):859-873.

3. Cao BJ, et al. Eur J Pharmacol. 1997 Sep 24;335(2-3):117-25.

4. Root DH, et al. J Neurosci. 2015 Feb 25;35(8):3460-9.

L 741742 hydrochloride (L-741742;L741,742;L741742)

生物&药学活性

物理化学性质&存储条件

参考文献

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询单

L 741742 hydrochloride (L-741742;L741,742;L741742)

生物&药学活性

物理化学性质&存储条件

参考文献

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