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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Immune Checkpoints-L557-0155
L557-0155

Chemical Structure : L557-0155

CAS No.: 1115893-25-8

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L557-0155 (L 557-0155)

货号: PC-38587Not For Human Use, Lab Use Only.

L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    L557-0155 is a small molecule inhibitor of VSIG-8, prevents VSIG-8 binding to VISTA, promotes cytokine production and cell proliferation in PBMCs and suppresses melanoma growth.

    物理化学性质&存储条件

    分子量 422.869
    分子式 C22H19ClN4O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-(5-chloro-2-(pyridin-4-yl)-1H-indol-3-yl)-3-(3,5-dimethoxyphenyl)urea

    参考文献

    1. Wenting Chen, et al. Invest New Drugs. 2022 Apr 11. doi: 10.1007/s10637-022-01244-4.

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