L-NAME hydrochloride |CAS:51298-62-5 Probechem Biochemicals

Chemical Structure : L-NAME hydrochloride

CAS No.: 51298-62-5

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L-NAME hydrochloride (NG-Nitroarginine methyl ester hydrochloride)

货号: PC-45544Not For Human Use, Lab Use Only.

L-NAME hydrochloride is a widely used inhibitor of NO synthase (NOS) with IC50 of 70 uM for purified brain NOS.

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500 mg	￥880	In stock
1 g	￥1280	In stock
5 g		Get quote

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生物&药学活性

L-NAME hydrochloride is a widely used inhibitor of NO synthase (NOS) with IC50 of 70 uM for purified brain NOS.
L-NAME hydrochloride inhibits cGMP formation in endothelial cells with an IC50 of 3.1 µM (in the presence of 30 µM arginine) and reverses the vasodilation effects of acetylcholine in rat aorta rings.

物理化学性质&存储条件

分子量	269.686
分子式	C7H16ClN5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	H2O: ≥ 32 mg/mL
Chemical Name/SMILES	L-Ornithine, N5-[imino(nitroamino)methyl]-, methyl ester, hydrochloride (1:1)

参考文献

1. Pfeiffer S, et al. Br J Pharmacol. 1996 Jul;118(6):1433-40.

2. Lo HC, et al. PLoS One. 2016 Mar 23;11(3):e0151973.

3. Xiao H, et al. Oncotarget. 2017 May 2;8(18):29976-29983.

L-NAME hydrochloride (NG-Nitroarginine methyl ester hydrochloride)

生物&药学活性

物理化学性质&存储条件

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L-NAME hydrochloride (NG-Nitroarginine methyl ester hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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