L-870810 |CAS:410544-95-5 Probechem Biochemicals

Chemical Structure : L-870810

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L-870810 (L 870810;L870810)

货号: PC-70242Not For Human Use, Lab Use Only.

A potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.

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生物&药学活性

L-870810 is a potent, selective inhibitor of HIV integrase (IC50=8-15 nM) with potent antiviral activity in cell culture and good pharmacokinetic properties.
L-870810 exhibits broad-spectrum activity against WT and multidrug-resistant HIV-1, HIV-2, and SIV; orally bioavailable.

物理化学性质&存储条件

分子量	430.454
分子式	C20H19FN4O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(1,1-dioxothiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-8-hydroxy-1,6-naphthyridine-7-carboxamide

参考文献

1. Hazuda DJ, et al. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11233-8.

2. Zeng LF, et al. J Med Chem. 2012 Nov 26;55(22):9492-509.

3. Hombrouck A, et al. Antimicrob Agents Chemother. 2008 Jun;52(6):2069-78.

L-870810 (L 870810;L870810)

生物&药学活性

物理化学性质&存储条件

参考文献

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L-870810 (L 870810;L870810)

生物&药学活性

物理化学性质&存储条件

参考文献

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