L-701324 | NMDAR antagonist | Probechem Biochemicals

Chemical Structure : L-701324

CAS No.: 142326-59-8

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L-701324 (L-701,324, L701324)

货号: PC-45532Not For Human Use, Lab Use Only.

L-701324 (L-701,324) is a potent, orally active antagonist at the glycine modulatory site on NMDA receptor with IC50 of 2 nM.

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10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥2980	In stock
100 mg	￥4780	In stock
250 mg		Get quote

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生物&药学活性

L-701324 (L-701,324) is a potent, orally active antagonist at the glycine modulatory site on NMDA receptor with IC50 of 2 nM.
L-701324 is a potent, p.o. active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents.

物理化学性质&存储条件

分子量	363.7938
分子式	C21H14ClNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 34 mg/mL
Chemical Name/SMILES	2(1H)-Quinolinone, 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-

参考文献

1. Kulagowski JJ, et al. J Med Chem. 1994 May 13;37(10):1402-5.

2. Bristow LJ, et al. J Pharmacol Exp Ther. 1996 Nov;279(2):492-501.

3. Hutson PH, et al. Eur J Pharmacol. 1997 May 20;326(2-3):127-32.

L-701324 (L-701,324, L701324)

生物&药学活性

物理化学性质&存储条件

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L-701324 (L-701,324, L701324)

生物&药学活性

物理化学性质&存储条件

参考文献

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