L-365260 |CAS:118101-09-0 Probechem Biochemicals

Chemical Structure : L-365260

加入收藏

L-365260 (L 365260;L365260)

货号: PC-70239Not For Human Use, Lab Use Only.

L-365260 (L365260) is a potent, selective, orally active cholecystokinin receptor 2 (CCK2) antagonist with IC50 of 2 nM.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

L-365260 (L365260) is a potent, selective, orally active cholecystokinin receptor 2 (CCK2) antagonist with IC50 of 2 nM.
L-365260 displays >100-fold selecitvity over CCK1.
L-365260 antagonizes gastrin-stimulated acid secretion in mice (ED50 = 0.03 mg/kg), does not affect basal acid secretion and did not antagonize histamine- or carbachol-stimulated acid secretion.

物理化学性质&存储条件

分子量	398.46
分子式	C24H22N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[(3R)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)urea

参考文献

1. Kopin AS, et al. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5525-30.

2. Bock MG, et al. J Med Chem. 1989 Jan;32(1):13-6.

3. Lotti VJ, et al. Eur J Pharmacol. 1989 Mar 21;162(2):273-80.

L-365260 (L 365260;L365260)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

L-365260 (L 365260;L365260)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.