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首页-小分子抑制剂&激动剂-GPCR-Angiotensin Receptor-L-162313
L-162313

Chemical Structure : L-162313

CAS No.: 151488-11-8

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L-162313 (L-162,313)

货号: PC-27613Not For Human Use, Lab Use Only.

L-162313 (L-162,313) is a potent, selective non-peptide agonist of angiotensin II AT1 and AT2 receptors with IC50 of 1.1 and 2.0 nM, stimulates phosphoinositide hydrolysis in COS-7 cells transfected with the rat AT1 receptor with EC50 of 33 nM.

规格 价格 库存 数量
5 mg ￥1980 In stock
10 mg ￥3280 In stock
25 mg ￥5280 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

L-162313 (L-162,313) is a potent, selective non-peptide agonist of angiotensin II AT1 and AT2 receptors with IC50 of 1.1 and 2.0 nM, stimulates phosphoinositide hydrolysis in COS-7 cells transfected with the rat AT1 receptor with EC50 of 33 nM.

物理化学性质&存储条件

分子量 582.78
分子式 C30H38N4O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Butyl ((3-(4-((2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)phenyl)-5-isobutylthiophen-2-yl)sulfonyl)carbamate

参考文献

1. Kivlighn SD, et al. Am J Physiol. 1995 Mar;268(3 Pt 2):R820-3.

2. Wan Y, et al. J Med Chem. 2004 Mar 11;47(6):1536-46.

3. Kivlighn SD, et al. Am J Physiol. 1995 Mar;268(3 Pt 2):R820-3.

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