Kinetin riboside |CAS:4338-47-0 Probechem Biochemicals

Chemical Structure : Kinetin riboside

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Kinetin riboside (N6-Furfuryladenosine;FAdo)

货号: PC-42305Not For Human Use, Lab Use Only.

A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines.

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25 mg		Get quote
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250 mg		Get quote

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生物&药学活性

A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines; inhibits MiPaCa-2 cell proliferation with IC50 of 0.27 uM; induceds marked suppression of CCND2 transcription and rapidly suppresses cyclin D1 and D2 protein expression in primary myeloma cells and tumor lines, causing cell cycle arrest, tumor cell-selective apoptosis, and inhibition of myeloma growth in xenografted mice; also can activate PINK1 in cells independent of mitochondrial depolarization.

物理化学性质&存储条件

分子量	347.32598
分子式	C15H17N5O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	DMSO: ≥ 29 mg/mL
Chemical Name/SMILES	Adenosine, N-(2-furanylmethyl)-

参考文献

1. Osgerby L, et al. J Med Chem. 2017 Apr 27;60(8):3518-3524.

2. Tiedemann RE, et al. J Clin Invest. 2008 May;118(5):1750-64.

3. Hertz NT, et al. Cell. 2013 Aug 15;154(4):737-47.

4. Choi BH, et al. J Biol Chem. 2010 Mar 26;285(13):9770-9.

Kinetin riboside (N6-Furfuryladenosine;FAdo)

生物&药学活性

物理化学性质&存储条件

参考文献

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Kinetin riboside (N6-Furfuryladenosine;FAdo)

生物&药学活性

物理化学性质&存储条件

参考文献

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