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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-Ketanserin tartrate
Ketanserin tartrate

Chemical Structure : Ketanserin tartrate

CAS No.: 83846-83-7

Ketanserin tartrate (R41468 tartrate)

货号: PC-42654Not For Human Use, Lab Use Only.

A high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C.

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100 mg ¥560 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A high-affinity, non-selective antagonist of 5-HT2 receptor with Ki of 2-3 nM for 5-HT2A and 28 nM for 5-HT2C; also has a high affinity antagonist for the H1 receptor (Ki= 2 nM) and α1-adrenergic receptor (Ki=40 nM); an antihypertensive agent.

Hypertension

Approved

物理化学性质&存储条件

分子量 545.5136
分子式 C26H28FN3O9
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

H2O: 30 mg/mL (Need ultrasonic and warming)

Chemical Name/SMILES

2,4(1H,3H)-Quinazolinedione, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)

参考文献

1. Creed-Carson M, et al. Behav Brain Res. 2011 Jun 1;219(2):273-9.

2. Catafau AM, et al. J Cereb Blood Flow Metab. 2010 May;30(5):985-93.

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