Karyostatin 1A

Chemical Structure : Karyostatin 1A

加入收藏

货号: PC-21347Not For Human Use, Lab Use Only.

Karyostatin 1A is a small molecule inhibitor of importin beta with binding affinity (Kd=0.3 uM), selectively inhibits the importin α/β pathway.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Karyostatin 1A is a small molecule inhibitor of importin beta with binding affinity (Kd=0.3 uM), selectively inhibits the importin α/β pathway.
Karyostatin 1A specifically inhibit importin α/β mediated nuclear import in living cells.
Karyostatin 1A disrupts the binding of importin β to RanGTP.

物理化学性质&存储条件

分子量	971.22
分子式	C53H70N12O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N2-[[2-Methyl-1-(2-methylpropyl)-5-[2-(1-piperidinyl)acetyl]-1H-pyrrol-3-yl]carbonyl]-L-arginyl-N-[3-[[4-[1-[4-[(methylamino)carbonyl]phenyl]-1H-indazol-3-yl]benzoyl]amino]propyl]-N2-propylglycinamide

参考文献

1. Martin Hintersteiner, et al. ACS Chem Biol. 2010 Oct 15;5(10):967-79.

Karyostatin 1A

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Karyostatin 1A

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.