Chemical Structure : KWAR23
CAS No.:
货号: PC-Ab1111Not For Human Use, Lab Use Only.
KWAR23 is a monoclonal anti-human SIRPα antibody that binds to human SIRPα with high affinity, blocks the interaction of CD47 on one cell with SIRPα on a phagocytic cell. KWAR23 induces human macrophage-dependent phagocytosis in human tumor-derived cell lines, restores chemokine secretion in human macrophages in vitro, greatly augments myeloid cell-dependent killing of a collec-tion of hematopoietic and nonhematopoietic human tumor-derived cell lines..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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KWAR23 is a monoclonal anti-human SIRPα antibody that binds to human SIRPα with high affinity, blocks the interaction of CD47 on one cell with SIRPα on a phagocytic cell. KWAR23 induces human macrophage-dependent phagocytosis in human tumor-derived cell lines, restores chemokine secretion in human macrophages in vitro, greatly augments myeloid cell-dependent killing of a collec-tion of hematopoietic and nonhematopoietic human tumor-derived cell lines.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
KWAR23; Anti-Human SIRPα; Anti-Human SIRP alpha; Anti-human Signal regulatory protein alpha; Anti-human SHPS-1; Anti-human SIRPA |
1. 1, Nan Guo Ring, et al. Proc Natl Acad Sci U S A. 2017 Dec 5; 114(49): E10578–E10585. 2, Gabriela Andrejeva, et al. J Immunol. 2021 Feb 15; 206(4): 712–721. 3, Xiao Jia, et al. Int J Biol Sci. 2021; 17(13): 3281–3287.
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