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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-KT182
KT182

Chemical Structure : KT182

CAS No.: 1402612-62-7

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KT182 (KT-182)

货号: PC-20130Not For Human Use, Lab Use Only.

KT-182 (KT182) is a potent, selective, irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 of 1.7 nM.

规格 价格 库存 数量
5 mg ￥1380 In stock
10 mg ￥2180 In stock
25 mg ￥3780 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

KT-182 (KT182) is a potent, selective, irreversible α/β-hydrolase domain 6 (ABHD6) inhibitor with IC50 of 1.7 nM.
KT182 exhibits selectively for ABHD6 over other brain and liver serine hydrolases.
KT182 (1 mg/kg, i.p.) inhibits ABHD6 in liver and brain extracts in mice.

物理化学性质&存储条件

分子量 438.53
分子式 C27H26N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(4-(3'-(hydroxymethyl)-[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl)(2-phenylpiperidin-1-yl)methanone

参考文献

1. Ku-Lung Hsu, et al. J Med Chem. 2013 Nov 14;56(21):8270-9.

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