KT-362

Chemical Structure : KT-362

加入收藏

货号: PC-24336Not For Human Use, Lab Use Only.

KT-362 is a small molecule intracellular calcium antagonist, inhibits NE-induced contractions and IP accumulation.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

KT-362 is a small molecule intracellular calcium antagonist, inhibits NE-induced contractions and IP accumulation.
KT-362 (3 x 10(-6) to 3 x 10(-5) M) caused a dose-dependent decrease in the maximum upstroke velocity (Vmax) of the action potential without affecting the resting potential.
KT-362 has quinidine-like use-dependent inhibitory action on the fast sodium channel of cardiac muscles by the binding to the channel mainly during its activated state.
KT-362 also suppressed the slow action potential in K+ depolarized papillary muscles.

物理化学性质&存储条件

分子量	516.61
分子式	C26H32N2O7S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]-1-oxopropyl]-2,3,4,5-tetrahydro-1,5-benzothiazepine fumarate

参考文献

1. Ueyama N, et al. Chem Pharm Bull (Tokyo). 1997 Nov;45(11):1761-6.

2. Cheng YN, et al. J Pharmacol Exp Ther. 1994 Sep;270(3):851-7.

3. Kodama I, et al. J Pharmacol Exp Ther. 1991 Jul 1;258(1):332-8.

KT-362

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

KT-362

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.