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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-KSK67
KSK67

Chemical Structure : KSK67

CAS No.: 1638100-60-3

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KSK67 (KSK 67)

货号: PC-38713Not For Human Use, Lab Use Only.

KSK67 is a potent small molecule inhibitor of bacterial transcriptional activator PrfA with IC50 of 67 nM, reduces virulence factor expression in L. monocytogene.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    KSK67 is a potent small molecule inhibitor of bacterial transcriptional activator PrfA with IC50 of 67 nM, reduces virulence factor expression in L. monocytogene.

    物理化学性质&存储条件

    分子量 391.485
    分子式 C23H21NO3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (R)-8-cyclopropyl-7-((4-methylnaphthalen-1-yl)methyl)-5-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyridine-3-carboxylic acid

    参考文献

    1. Thao Thanh Tran, et al. PLoS Pathog. 2022 Jan 10;18(1):e1010166.

    2. James A D Good, et al. Cell Chem Biol. 2016 Mar 17;23(3):404-14.

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