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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-JNK-KRev-202
KRev-202

Chemical Structure : KRev-202

CAS No.: 3059122-53-8

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KRev-202 (KRev202)

货号: PC-27740Not For Human Use, Lab Use Only.

KRev-202 is a water-soluble prodrug (49 mg/mL) of the potent and selective JNK inhibitor Tanzisertib (CC-930, CC930), prevent ischemia-induced acute kidney injury (AKI).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

KRev-202 is a water-soluble prodrug (49 mg/mL) of the potent and selective JNK inhibitor Tanzisertib (CC-930, CC930), prevent ischemia-induced acute kidney injury (AKI).

物理化学性质&存储条件

分子量 574.40
分子式 C21H24F3N6O5P.2Na
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1S,4r)-4-((9-((S)-tetrahydrofuran-3-yl)-8-((2,4,6-trifluorophenyl)amino)-9H-purin-2-yl)amino)cyclohexyl dihydrogen phosphate, sodium salt

参考文献

1. Nikolic-Paterson DJ, et al. Front Pharmacol. 2026 Jan 30;16:1667221.

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