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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Autotaxin-KR-40795
KR-40795

Chemical Structure : KR-40795

CAS No.:

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KR-40795 (KR40795)

货号: PC-23311Not For Human Use, Lab Use Only.

KR-40795 is a novel small molecule autotaxin (ATX) inhibitor with IC50 of 0.13 uM, binds to the allosteric tunnel and hydrophobic pocket of ATX.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

KR-40795 is a novel small molecule autotaxin (ATX) inhibitor with IC50 of 0.13 uM, binds to the allosteric tunnel and hydrophobic pocket of ATX.

物理化学性质&存储条件

分子量 461.90
分子式 C26H20ClNO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

methyl (Z)-4-((2-((1-(3-chlorophenyl)-2,5-dioxopyrrolidin-3-ylidene)methyl)phenoxy)methyl)benzoate

参考文献

1. Hyeong Lee S, et al. Bioorg Med Chem Lett. 2024 Oct 28:130006.

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