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首页-小分子抑制剂&激动剂-Apoptosis-Fas Receptor-KR-33494
KR-33494

Chemical Structure : KR-33494

CAS No.: 1021497-97-1

KR-33494 (KM-819, KR33494)

货号: PC-62703Not For Human Use, Lab Use Only.

KM-819 (KR-33493) is a potent small molecule inhibitor of FAF1 (FAS-associated factor 1), inhibits Fas-mediated cell death.

规格 价格 库存 数量
10 mg ¥1280 In stock
25 mg ¥2180 In stock
50 mg ¥3780 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

KM-819 (KR-33493) is a potent small molecule inhibitor of FAF1 (FAS-associated factor 1), inhibits Fas-mediated cell death.
KM-819 (KR-33493) has shown potential for preventing dopaminergic neuronal cell death, promoting the degradation of α-synuclein and preventing its accumulation.

物理化学性质&存储条件

分子量 460.346
分子式 C20H18BrN3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-[[2-[(4-bromophenyl)thio]acetyl]amino]-1-(2-phenylethyl)-1H-pyrazole-3-carboxylic acid

参考文献

1. Yoo SE, et al. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1169-72.

2. Suh J, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6362-5.

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