KPT-8602 Z-isomer | CRM1 inhibitor | Probechem Biochemicals

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Exportin-1 (CRM1,XPO1)-KPT-8602 Z-isomer

Chemical Structure : KPT-8602 Z-isomer

CAS No.: 1642300-78-4

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KPT-8602 Z-isomer (Eltanexor Z-isomer, KPT8602 Z-isomer)

货号: PC-42151Not For Human Use, Lab Use Only.

KPT-8602 Z-isomer is the Z-isomer of Eltanexor (KPT-8602), which is a second-generation SINE with markedly reduced brain penetration compared to selinexor.

规格	价格	库存
5 mg	￥2380	In stock
10 mg	￥3680	In stock
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100 mg		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

KPT-8602 Z-isomer is the Z-isomer of Eltanexor (KPT-8602), which is a second-generation SINE with markedly reduced brain penetration compared to selinexor.

物理化学性质&存储条件

分子量	428.2913
分子式	C17H10F6N6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO
Chemical Name/SMILES	5-Pyrimidineacetamide, α-[[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]methylene]-, (αZ)-

参考文献

1. Etchin J, et al. Leukemia. 2017 Jan;31(1):143-150.

2. Hing ZA, et al. Leukemia. 2016 Dec;30(12):2364-2372.

3. Vercruysse T, et al. Clin Cancer Res. 2017 May 15;23(10):2528-2541.

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KPT-8602 Z-isomer (Eltanexor Z-isomer, KPT8602 Z-isomer)

生物&药学活性

物理化学性质&存储条件

参考文献

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KPT-8602 Z-isomer (Eltanexor Z-isomer, KPT8602 Z-isomer)

生物&药学活性

物理化学性质&存储条件

参考文献

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