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首页-小分子抑制剂&激动剂-Immunology/Inflammation-IRAK-KME-3859
KME-3859

Chemical Structure : KME-3859

CAS No.: 2968466-04-6

KME-3859 (KME3859)

货号: PC-21202Not For Human Use, Lab Use Only.

KME-3859 is a potent, selective IRAK4 inhibitor with IC50 of 5 nM, 100-fold selective over IRAK1.

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5 mg ¥4280 In stock
10 mg ¥7280 In stock
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纯度 & COA & 质检文件 纯度: 99.16% (HPLC) Select Batch:

生物&药学活性

KME-3859 is a potent, selective IRAK4 inhibitor with IC50 of 5 nM, 100-fold selective over IRAK1.

物理化学性质&存储条件

分子量 323.40
分子式 C18H21N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-6-(6-methoxyimidazo[1,2-a]pyridin-3-yl)-N-(piperidin-3-yl)pyridin-2-amine

参考文献

1. Bennett J, et al. Blood. 2023 Sep 14;142(11):989-1007.

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