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首页-小分子抑制剂&激动剂-Others-Other Targets-KL101
KL101

Chemical Structure : KL101

CAS No.: 396721-89-4

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KL101 (KL 101)

货号: PC-49458Not For Human Use, Lab Use Only.

KL101 (KL 101) is a isoform-selective small molecule stabilizer of Cryptochrome 1 (CRY1).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    KL101 (KL 101) is a isoform-selective small molecule stabilizer of Cryptochrome 1 (CRY1).
    KL101 showed selectivity over CRY2, and no or only minor effects on CKIδ, CKIα and CK2 activities in vitro.

    物理化学性质&存储条件

    分子量 377.506
    分子式 C22H23N3OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(2-(2,4-dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-3,4-dimethylbenzamide

    参考文献

    1. Miller S, et al. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2026191118.

    2. Miller S, et al. Nat Chem Biol. 2020 Jun;16(6):676-685.

    3. Iida M, et al. J Biochem. 2022 May 11;171(5):501-507.

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